Postdoc position in cancer neuroimmunology

The Department of Biomedicine is a joint effort between the University of Basel and the University Hospitals Basel. It unites basic and clinical scientists to advance our understanding of health and disease and to develop pioneering therapies benefiting the lives of patients in areas of unmet need.

With more than 70 research groups and 800 employees, the Department of Biomedicine is the largest department at the University. We are located in the heart of Basel at 6 different locations. Be part of our future!

A postdoc position is available in the laboratory of Professor Momo Bentires-Alj at the Department of Biomedicine (DBM) in Basel, Switzerland. The successful candidate will work on breast cancer brain metastasis and interactions of cancer cells with brain resident and infiltrating immune cells.

Selected publications of our lab include: 1- Glucocorticoids promote breast cancer metastasis. Obradovic MMS, et al., Nature 2019. 2- Hepatic stellate cells suppress NK cell-sustained breast cancer dormancy. Correia AL, et al. Nature 2021. 3- Feed-forward loops between metastatic cancer cells and their microenvironment-the stage of escalation. Baumann Z, Auf der Maur P, Bentires-Alj M. EMBO Mol Med. 2022. 4- N-acetylcysteine overcomes NF1 loss-driven resistance to PI3Ka inhibition in breast cancer. Auf der Maur P. et al. Cell Rep Med. 2023.
The successful candidate will work on molecular and cellular mechanisms underlying cancer cell response to brain microenvironment using mouse models, heterotypic cultures and patient samples. The candidate will implement a variety of OMICs at single cell and spatial level, as well as standard and advanced molecular and cellular biology approaches.
A strong experience in neuroimmunology or neuro-oncology. Expertise in single cell OMICs, 3D heterotypic cultures, and/or mouse work, intravital imaging is a plus. The candidate should be creative and highly motivated, should contribute to the lab by also being well-organized, cooperative and fluent in English.
A stimulating, challenging and interdisciplinary translational research environment, state-of-the-art technologies and core facilities, and attractive employment conditions. The DBM is an international institute pursuing basic, translational and clinical research, with access to cutting-edge core facilities and in the heart of multicultural city of Basel.

Lab website: https://bentireslab.org/
Application / Contact

Please upload your CV, a summary of your research experience and interests, techniques that you are competent in, and the contact details of three referees including your current PI at: https://biped.dbm.unibas.ch/apply/postdoc_position_in_cancer_neuroimmunology_start_january_2025

Application deadline: Applications will be reviewed as they arrive.

Contact: thmrjobapplication-dbm@unibas.ch