CBS- Postdoctoral Angiogenesis pathways Proteomics and Drug Development -11856

The Chemical and Biochemical Sciences-Green Process Engineering at the University of Mohammed VI Polytechnic Benguerir Morocco seeks Postdoctoral applicants in Proteomics and Drug Development. 

Job/Project Description:

Angiogenesis, the formation of new blood vessels, is crucial angiogenesis in tumor growth, proliferation, invasion, and metastasis. Advances in molecular biology have identified key biomolecules involved in this process, making anti-angiogenic treatments a promising cancer therapy strategy. Common treatments include monoclonal antibodies and tyrosine kinase inhibitors targeting the VEGF pathway. However, challenges like adverse events, drug resistance, tumor recurrence, and lack of biomarkers limit their effectiveness. Further research into angiogenesis mechanisms, drug development, and combination therapies is needed to enhance therapeutic outcomes. In recent years, a significant research focus has been on combining angiogenic inhibitors with immune checkpoint inhibitors. This approach has shown improved clinical benefits in hepatocellular carcinoma and renal cell carcinoma patients treated with a combination of PD-1 and VEGFR-2 inhibitors compared to monotherapies.

To addresses the challenges of anti-angiogenic treatment and explores emerging strategies to enhance its therapeutic benefits. We are focusing on the development of novel anti-angiogenic drugs against specific biomarkers as a potential clinical candidate.

To meet our objectives, we have collaborated with colleagues from Canadian, USA, and European universities, and we are equipped with OMICS state-of-the-art technologies. 

Fellowship

• Competitive international compensation and health insurance
  Expected activities.

• Conduct research as part of the project team.

Applicant requirements

• Ph.D. in bioinformatics, proteomics, drug design and development, genomics, mathematics, computer science, or related fields

• Complete CV

• Short research statement (summary)

• Interest in intracellular organelle/cell biology, signal transduction, proteomics, drug design, or related fields

• Good knowledge of cell biological and molecular biological methods

• Experience in bioinformatics tools related to proteomics and drug design.

• Aptitude for teamwork, problem-solving solving, and collaborative relationships

• Verbal and written skills in English

• Positive attitude in changing fast-paced environments.