King Abdullah University of Science and Technology (KAUST)

Postdoctoral fellow in cryo-EM of human DNA replication

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Highly motivated candidates are invited to apply for a 3-year postdoctoral position in the laboratory of Dr. Alfredo De Biasio in the Biological and Environmental Sciences and Engineering (BESE) Division at the King Abdullah University of Science and Technology (KAUST) (https://www.kaust.edu.sa/en/study/faculty/alfredo-de-biasio). The project investigates the structure and function of key protein complexes operating in human DNA replication using cryo-Electron Microscopy (cryo-EM). For examples of our recent work see: Lancey et al., Nature Commun, 12(1):6095 (2021); Lancey et al., Nature Commun., 11(1):1109 (2020). The successful candidate will join a vibrant community of structural biologists, biochemists and biophysicists.

The BESE Division at KAUST offers a unique combination of an intellectually stimulating environment and access to world-class laboratories, instrumentation, and generous funding schemes. KAUST provides outstanding structural biology research facilities, including a Titan KRIOS G4 [with cold FEG illumination, Ceta D camera, Selectris X and Falcon 4 and phase plate and access to powerful GPU computer clusters], Titan KRIOS G1 [with phase plates, Quantum GIF Gatan filter (model 968), K2 Summit direct detector and access to powerful GPU computer clusters], NMR spectrometers (600, 700, 800 and 950 MHz) and an in-house X-ray source. KAUST facilities also include state-of-the-art core laboratories in Genomics, Proteomics, Imaging & Characterization, Extreme Computing and Informatics.

KAUST is an international, graduate research university dedicated to advancing science and technology through interdisciplinary research, education, and innovation. KAUST attracts top international faculty, scientists, engineers and students to conduct curiosity-driven and goal-oriented research to address the world’s most pressing scientific and technological challenges. Located in Saudi Arabia, on the eastern shores of the Red Sea, KAUST provides an award-winning campus to live, work, study and play, and offers superb research facilities, with guaranteed baseline research funding, infrastructure support, entrepreneurship opportunities and internationally competitive salaries. For more information about KAUST, please visit http://www.kaust.edu.sa. More information about the BESE Division and the Bioscience Program is available at http://bese.kaust.edu.sa.  

Informal enquiries are welcomed and should be made to Dr. Alfredo De Biasio on +966 012 8084646 or alfredo.debiasio@kaust.edu.sa

The Research Associate will be expected to take a leading role in developing and carrying out the research programme. The project will require strong skills in cryo-EM sample preparation, and cryo-EM data acquisition and processing. The ideal candidate will have a PhD in structural biology, biochemistry, molecular biology or a related discipline, and experience in the field of single-particle cryo-EM. A high level of proficiency in English and excellent written and verbal communication skills are essential requirements for this position.

Please provide the required documentation:
- CV
- cover letter
- publication list
- contact details of 2 references

DESCRIPCIÓN DEL PUESTO

Título
Postdoctoral fellow in cryo-EM of human DNA replication
Ubicación
King Abdullah University of Science and Technology Thuwal, Arabia Saudí
Publicado
2022-01-30
Fecha límite de aplicación
Unspecified
Tipo de trabajo
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